Hydrolysis of Polyadenylic Acid by Pancreatic Ribonuclease
نویسندگان
چکیده
منابع مشابه
Peptides obtained by peptic hydrolysis of performic acid-oxidized ribonuclease.
In a continuation of the structural studies on ribonuclease reported in earlier papers (l-3), the products resulting from the action of pepsin on performic acid-oxidized ribonuclease have been examined by means of ion exchange chromatography. Eight peptides have been isolated in purified form and their amino acid compositions have been determined. In a following communication (4), a partial str...
متن کاملPeptides obtained by tryptic hydrolysis of performic acid-oxidized ribonuclease.
In the present study, the chemical structure of ribonuclease has been investigated by the use of trypsin as a reagent. for the hydrolysis of specific peptide bonds in the oxidized protein, and the resulting peptides have been separated and analyzed by ion exchange chromatography. The investigations of Anfinsen, Redfield, Choate, Page, and Carroll (3) have shown that ribonuclease consists of a s...
متن کاملPeptides Obtained by Peptic Hydrolysis of Performic Acid-oxidized Ribonuclease
In a continuation of the structural studies on ribonuclease reported in earlier papers (l-3), the products resulting from the action of pepsin on performic acid-oxidized ribonuclease have been examined by means of ion exchange chromatography. Eight peptides have been isolated in purified form and their amino acid compositions have been determined. In a following communication (4), a partial str...
متن کاملMice by Polyadenylic Acid: Polyuridylic Acid Complex
The effect of polyadenylic acid: polyuridylic acid complex (poly A: U) on immunization was investigated in mice vaccinated by killed Brucella melitensis cells suspended in incomplete adjuvant or in saline. Addition of 300 ,ug of poly A:U to vaccines rendered 3 X 108 B. melitensis cells in saline as immunogenic as 3 X 10"1 cells in oil adjuvant against a severe B. abortus challenge. In the mouse...
متن کاملThe Isolation of Mononucleotides after Hydrolysis of Ribonucleic Acid by Crystalline Ribonuclease* by Hubert
Since the discovery by Jones (1) of a thermostable enzyme in the pancreas, capable of hydrolyzing ribonucleic acid without the release of either phosphoric acid or purine bases, the evidence as to the nature of its action has been extremely conflicting. Jones and Perkins isolated four mononucleotides from enzyme-treated nucleic acid and concluded that the action of the enzyme consisted in break...
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ژورنال
عنوان ژورنال: Journal of Biological Chemistry
سال: 1960
ISSN: 0021-9258
DOI: 10.1016/s0021-9258(18)64633-2